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How Polyphenols Affect Memory and Learning in the Brain :

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How Polyphenols Affect Memory and Learning in the Brain  How Polyphenols Affect Memory and Learning in the Brain   Polyphenols are natural compounds found in plants that have various health benefits. They can act as antioxidants, anti-inflammatory agents, and modulators of cellular signaling. In this article, we will focus on how polyphenols affect memory and learning processes in the brain, especially in the hippocampus, which is the main region responsible for long-term memory formation. The Role of CREB and BDNF Proteins : One of the mechanisms by which polyphenols influence memory and learning is by regulating the activity of two proteins: CREB (Camp Response Element Binding) and BDNF (Brain-Derived Neurotrophic Factor). These proteins are involved in neuronal plasticity, which is the ability of neurons to change their structure and function in response to stimuli. Neuronal plasticity is essential for memory consolidation and retrieval. CREB is a transcript...